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Possible Answers:
PPL.
Last seen on: The New Yorker Tuesday, 26 December 2023 Crossword Answers
Random information on the term “PPL”:
4Q28
5493
19041
ENSG00000118898
ENSMUSG00000039457
O60437
Q9R269
NM_002705
NM_008909
NP_002696
NP_032935
Periplakin is a protein that in humans is encoded by the PPL gene.
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
PPL (gene) has been shown to interact with Keratin 8 and Envoplakin.