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looking at this crossword definition, it has 33 letters.
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Possible Answers:
WITH.
Last seen on: USA Today Crossword – Nov 13 2022
Random information on the term “'What's up ___ that?'”:
E, or e, is the fifth letter and the second vowel letter in the modern English alphabet and the ISO basic Latin alphabet. Its name in English is e (pronounced /ˈiː/); plural ees, Es or E’s. It is the most commonly used letter in many languages, including Czech, Danish, Dutch, English, French, German, Hungarian, Latin, Latvian, Norwegian, Spanish, and Swedish.
hillul
The Latin letter ‘E’ differs little from its source, the Greek letter epsilon, ‘Ε’. This in turn comes from the Semitic letter hê, which has been suggested to have started as a praying or calling human figure (hillul ‘jubilation’), and was most likely based on a similar Egyptian hieroglyph that indicated a different pronunciation. In Semitic, the letter represented /h/ (and /e/ in foreign words); in Greek, hê became the letter epsilon, used to represent /e/. The various forms of the Old Italic script and the Latin alphabet followed this usage.
'What's up ___ that?' on Wikipedia
Random information on the term “WITH”:
Carl Johannes With (December 11, 1877 – June 16, 1923) was a Danish doctor and arachnologist, specialising in pseudoscorpions and mites.
With was born in Lemvig to Nicolai Rasmus With and his wife Rasmine Sophie Dorothea With, but was orphaned by the age of five. With married Inge Kiørboe on July 1, 1909, and together they had three children. With died in 1923 in Skibstrup, in the parish of Hellebæk (Helsingør Municipality), while still working on a dissertation on lupus.
After studying at the University of Oxford in 1896, With studied natural history and geography, and in 1904, undertook a research trip to England and in particular, the collections of the British Museum. In 1905, he won the Schibbye’ske Præmie (Schibbye Prize) for his work on Opilioacariformes.
With was not confident that zoology could provide a secure future, so he studied medicine, including time at the Institut Pasteur in Paris. He took part in the Franco–Danish leprosy expedition to the Danish West Indies in 1909, graduated in 1911, and then started to work as a dermatologist at the University Hospital and Municipal Hospital in Copenhagen.