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Possible Answers:
UBE.
Last seen on: –The New Yorker Tuesday, 12 December 2023 Crossword Answers
LA Times Crossword, Thu, Jan 12, 2023
Random information on the term “Purple yam”:
One of the major human migration events was the maritime settlement of the islands of the Indo-Pacific by the Austronesian peoples, believed to have started from at least 5,500 to 4,000 BP (3500 to 2000 BCE). These migrations were accompanied by a set of domesticated, semi-domesticated, and commensal plants and animals transported via outrigger ships and catamarans that enabled early Austronesians to thrive in the islands of Maritime Southeast Asia (also known as ‘Island Southeast Asia’. e.g.: Philippines, Indonesia), Near Oceania (Melanesia), Remote Oceania (Micronesia and Polynesia), Madagascar, and the Comoros Islands.
They include crops and animals believed to have originated from the Hemudu and Majiabang cultures in the hypothetical pre-Austronesian homelands in mainland China, as well as other plants and animals believed to have been first domesticated from within Taiwan, Maritime Southeast Asia, and New Guinea. Some of these plants are sometimes also known as “canoe plants”, especially in the context of the Polynesian migrations. Domesticated animals and plants introduced during historic times are not included.
Random information on the term “UBE”:
Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target a protein for degradation via a proteasome. This covalent bond of ubiquitin or ubiquitin-like proteins to targeted proteins is a major mechanism for regulating protein function in eukaryotic organisms. Many processes such as cell division, immune responses and embryonic development are also regulated by post-translational modification by ubiquitin and ubiquitin-like proteins.
Ubiquitin-activating enzyme (E1) starts the ubiquitination process (Figure 1). The E1 enzyme, along with ATP, binds to the ubiquitin protein. The E1 enzyme then passes the ubiquitin protein to a second protein, called ubiquitin carrier or conjugation protein (E2). The E2 protein complexes with a ubiquitin protein ligase (E3). This ubiquitin protein ligase recognizes which protein needs to be tagged and catalyzes the transfer of ubiquitin to that protein. This pathway repeats itself until the target protein has a full chain of ubiquitin attached to itself.