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Possible Answers:
CRT.
Last seen on: Wall Street Journal Crossword – January 14 2023 – Alternate Endings
Random information on the term “CRT”:
3POW, 2CLR, 3DOW, 3POS
811
12317
ENSG00000179218
ENSMUSG00000003814
P27797
P14211
NM_004343
NM_007591
NP_004334
NP_031617
Calreticulin also known as calregulin, CRP55, CaBP3, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 (ERp60) is a protein that in humans is encoded by the CALR gene.
Calreticulin is a multifunctional soluble protein that binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. The Ca2+ is bound with low affinity, but high capacity, and can be released on a signal (see inositol trisphosphate). Calreticulin is located in storage compartments associated with the endoplasmic reticulum and is considered an ER resident protein.
The term “Mobilferrin” is considered to be the same as calreticulin by some sources.
Calreticulin binds to misfolded proteins and prevents them from being exported from the endoplasmic reticulum to the Golgi apparatus.