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Possible Answers:
IRE.
Last seen on: The Atlantic Saturday, 27 May 2023 Crossword Answers
Random information on the term “Burning sensation”:
Chemotherapy-induced peripheral neuropathy (CIPN) is a nerve-damaging side effect of antineoplastic agents in the common cancer treatment, chemotherapy. CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. These symptoms can impair activities of daily living, such as typing or dressing, reduce balance, and increase risk of falls and hospitalizations. They can also give cause to reduce or discontinue chemotherapy. Researchers have conducted clinical trials and studies to uncover the various symptoms, causes, pathogenesis, diagnoses, risk factors, and treatments of CIPN.
CIPN symptoms manifest themselves as deficits in sensory, motor, and/or autonomic functions of varying intensity, and they can significantly reduce a patient’s functional quality of life. Sensory symptoms affecting the hands and feet generally develop first. Sensory side effects are caused when nerves in the most distal parts of the limbs are damaged. Patients may experience numbness, tingling, altered touch sensation, gait and balance disturbances, burning pain, thermal allodynia or hyperalgesia, impaired vibration sense, extreme temperature sensitivity, paresthesia, and/or dysesthesia as part of sensory damage. On the other hand, motor symptoms are less frequently seen as sensory symptoms. Motor symptoms of CIPN can include cramping, distal weakness, difficulty handling small objects, and impaired movements. In severe cases, motor symptoms can lead to complete immobilization and severe disability. Finally, autonomic symptoms usually involve orthostatic hypotension, constipation, and altered urinary function. A patient experiencing CIPN symptoms may have difficulty performing daily functionalities like walking, dressing themselves, writing, typing, and other activities related to the hands and feet.
Burning sensation on Wikipedia
Random information on the term “IRE”:
Ire is the fifth studio album by Australian metalcore band Parkway Drive. It was released on 25 September 2015 through Resist and Epitaph Records, and was streamed online on 20 September. The album was produced by George Hadji-Christou. The band sought to change their established style with Ire, and reviewers have noted the inclusion of new influences.
At the J Awards of 2015, the album was nominated for Australian Album of the Year.
Ire marks a change from the style established on the band’s previous records. In an interview with Music Feeds, frontman Winston McCall stated: “…in the past … [when] we took the influence we had and then we put it into the context of what the Parkway Drive formula was, then that influence got mixed or buried or lost amongst the other stuff. This time around when any influence or unorthodox idea came about we simply ran with it in its whole form and tried to form a concept around that, rather than try to squash it into the pre-existing formula. That became basically the conceptual approach for making this entire record. … When you’re playing the same style of riff, the same drumming, the same vocals and same breakdowns for ten years, what point is there in people listening to your new record or even recording one if it sounds the exact same as the last one?”