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Possible Answers:
NAGS.
Last seen on: The New Yorker Tuesday, March 14, 2023 Crossword Answers
Random information on the term “Bugs”:
Bugs Bunny is an animated cartoon character created in the late 1930s at Warner Bros. Cartoons (originally Leon Schlesinger Productions) and voiced originally by Mel Blanc. Bugs is best known for his featured roles in the Looney Tunes and Merrie Melodies series of animated short films, produced by Warner Bros. Earlier iterations of the character first appeared in Ben Hardaway’s Porky’s Hare Hunt (1938) and subsequent shorts before Bugs’s definitive characterization debuted in Tex Avery’s A Wild Hare (1940). Bob Givens and Robert McKimson are credited for defining Bugs’s design.
Bugs is an anthropomorphic gray and white rabbit or hare who is characterized by his flippant, insouciant personality. He is also characterized by a Brooklyn accent, his portrayal as a trickster, and his catch phrase “Eh…What’s up, doc?”. Through his popularity during the golden age of American animation, Bugs became an American cultural icon and Warner Bros.’ official mascot.
Random information on the term “NAGS”:
Carbamoyl phosphate synthetase I is a ligase enzyme located in the mitochondria involved in the production of urea. Carbamoyl phosphate synthetase I (CPS1 or CPSI) transfers an ammonia molecule to a molecule of bicarbonate that has been phosphorylated by a molecule of ATP. The resulting carbamate is then phosphorylated with another molecule of ATP. The resulting molecule of carbamoyl phosphate leaves the enzyme.
In E. coli the single CPS that carries out the functions of CPSI and CPSII is a heterodimer with a small subunit and a larger subunit with about 382 and 1073 amino acid residues in size, although in mammals (and other vertebrates) the CPSI protein is encoded by a single gene. The small subunit contains one active site for the binding and deamination of glutamine to make ammonia and glutamate. The large subunit contains two active sites, one for the production of carboxyphosphate, and the other for the production of carbamoyl phosphate. Within the large subunit there are two domains (B and C) each with an active site of the ATP-grasp family. Connecting the two subunits is a tunnel of sorts, which directs the ammonia from the small subunit to the large subunit.