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“Angels in America” subject

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Possible Answers:
AIDS.

Last seen on: The New Yorker Monday, February 13, 2023 Crossword Answers

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The human immunodeficiency viruses (HIV) are two species of Lentivirus (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype.

AIDS on Wikipedia

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